Deliver more energy, where needed
Browse all Indena’s documents about products, events, company information and so much more.
Go to section
NUTRACEUTICALS
Ubiqsome®
CoQ10 Phytosome™
Scroll to see more
NEW SCIENTIFIC EVIDENCE
A natural ally for cardiovascular health
A human study on endothelial protection confirms Ubiqsome®’s potential for cardiovascular health.1
When oxidative stress is an issue, Ubiqsome® is the answer. The latest clinical evidence shows that Ubiqsome® could fight oxidation also at endothelial level, where it may greatly contribute to the wellbeing of the cardiovascular system.1
Both acute and chronic supplementation with Ubiqsome® are effective in optimizing plasmatic TAC (total antioxidative capacity) and endothelial reactivity. 1
Explore the results
Overview
We’ve set the absolute advantage
Coenzyme Q10 (CoQ10), also known as ubiquinone or ubidecarenone, is a key endogenous factor in cell energy production. It has shown protective properties against oxidative stress, mainly in skeletal and heart muscles and, more recently, at the endothelial level.1,2
CARDIOVASCULAR OXIDATIVE STRESS PROTECTION
Endothelial function is an important early marker for cardiovascular risk, reflecting the ability of the endothelial layer to fight early pro-atherosclerosis conditions. Since endothelial dysfunction is primarily driven by ROS and NO deficiency, the antioxidant potential of Ubiqsome® could be a valuable ally to maintain the endothelium in good health. s beyond any other available on the market.
A recently published study on healthy young people has confirmed this hypothesis, showing an improvement of endothelial function in both acute and chronic settings after the administration of Ubiqsome®.1
MUSCULAR OXIDATIVE STRESS PROTECTION
Reactive oxygen species (ROS) are overproduced during intense training and exercise, contributing to muscular stress and damage. A study on healthy, aging runners showed that the administration of Ubiqsome® optimizes plasmatic and muscular CoQ10 concentration, counteracting oxidative stress right where it’s needed.3
Ubiqsome® into action
Ubiqsome® confers antioxidant protection for the management of certain health challenges, also tied to aging.2
It is a food-grade bioavailable form of coenzyme Q10 that guarantees significant physiological CoQ10 plasma levels after a single dose and after 2 weeks of treatment.2
It fights oxidation from the inside thanks to its unique properties: Ubiqsome® increases CoQ10 in innermost cellular environments, such as mitochondria, as shown by a recent in-vitro study.
Furthermore, a dose-related profile is observed and administration is well tolerated.2
Phytosome™
Find out how Ubiqsome®
is one step beyond
Ubiqsome® is the only CoQ10 formulation to benefit from Indena’s Phytosome™ delivery system, a strategy that optimizes the bioabsorption of this important cofactor.
Outstanding clinical results have been accomplished, thanks to the innovative Phytosome™ technology platform, also in enhancing one of CoQ10’s limiting factors: oral bioavailability. The coenzyme’s high molecular weight and its very low aqueous solubility usually make it unsuitable for the oral administration route: that’s where the Phytosome™ delivery system is particularly useful, improving and optimizing the bioabsorption phase.2
In addition, Ubiqsome® is the first CoQ10 formulation to have been tracked down to its real target, the inner space of cells where it is needed.
See through science
Peer-reviewed science on Ubiqsome®
Here you can find more scientific evidence for your review.
ACCESS NOWBibliography
1Cicero et al.; Biofactors (2022): 1-6.
2Petrangolini et al.; Current Drug Delivery (2019).
3Drobnic et al.; J Food Sci Nutr Res (2020); 3 (4): 262-275.
4Rizzardi et al.; Antioxidants (2021); 10.6: 927.
UBIQSOME® at a glance
Why choose Ubiqsome®?
01.
Is the optimized delivery form of coenzyme Q10, formulated with Phytosome™ technology.
02.
Supported by human-double pharmacokinetic and human-efficacy studies.
03.
Optimizes CoQ10 plasma levels in a dose-dependent fashion and shows 14-fold higher solubility in simulated intestinal fluids.
04.
Optimizes CoQ10 levels in human muscle cells.
05.
Is the first and only CoQ10 formulation on the market to have been tracked from oral administration down to its single, real target: the inner space of cells.
06.
Offers great potential for nutraceutical integration in any situation that requires an effective contribution of coenzyme Q10 for the wellbeing and balance of the body.
07.
Can be a cost-effective solution thanks to optimized bioabsorption – allowing for lower CoQ10 content without relying upon expensive capsulating technologies, as well as industrial scalability and versatile finished oral dosage forms.
08.
Supports the endothelial function’s ability to fight oxidation.
09.
Could be a promising ingredient for cardiovascular health, able to protect from cardiovascular risk factors.
Technical Data
Common Name
Ubiqsome® - CoQ10 Phytosome™
Type
Ingredient with optimized bioabsorption
Plant source
-
Health benefit
Cardiovascular Health, Cellular energy support, Heart health, Support intensive exercise, Anti-ageing, Antioxidant protection
Patent & Trademark
Ubiqsome is patented (EP3307244).
Ubiqsome is a trademark of Indena S.p.A. The use of Indena’s trademarks is subject Indena’s authorization and to the acceptance of the terms and conditions set out in the Trademark Usage Guidelines downloadable HERE.
Specifications
Standardized to contain 18-22% of coenzyme Q10
Recommended dose and use
Up to 500 mg/day. Ubiqsome® may be used in a variety of supplement formulations.
Assay
18-22% of coenzyme Q10 by HPLC
Broad category
Cell bioenergetics suport, sports nutrition, healthy aging, heart & cardiovascular health, brain health
These statements may not comply with your country’s laws and regulations or with Reg. EC n. 1924/2006 and have not been evaluated by the Food and Drug Administration. The products are not intended to diagnose, treat, cure or prevent any disease. Marketers of finished products containing this ingredient are responsible for ensuring compliance with the applicable legal framework.
UBIQSOME® documents
